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Producto Referencia Descripción Formato PDF Detalles
CD2 Antibody (Clone RPA-2.10) 6250-100 CD2, a well-known T cell marker, is a surface antigen of the human T-lymphocyte lineage. Also known ... 100 µg N/D
CD2 Antibody (Clone RPA-2.10) » Descripción

CD2, a well-known T cell marker, is a surface antigen of the human T-lymphocyte lineage. Also known as the sheep erythrocyte receptor, CD2 is a 351 amino acid containing protein that contains an Ig-like C2 –type (immunoglobulin like) domain, an Ig-like V –type (immunoglobulin like) domain and a cytoplasmic domain implicated in T cell signaling. It interacts with CD2AP (CD2-associated protein) and PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1). CD2 mediates adhesion between T cells and other cell types by interacting with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1. Interaction between CD2 and its counter receptor, LFA3 (CD58), on opposing cells helps in immune recognition and facilitates contacts between helper T-lymphocytes and antigen-presenting cells as well as between cytolytic effectors and target cells. CD2 expression promotes chronic HBV infection and may also contribute to the hepatocyte damage. Expression of CD2 is common on all peripheral blood T cells, thymocytes, and also on some natural killer cells but not on B lymphocytes.

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Shipping: gel pack, Storage Temp.: -20 °C

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WB, FA (N), Flow (CS), IHC (frozen)

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Host & Isotype: Mouse IgG1, kappa, Species Reactivity: Human, Antibody Type: Monoclonal

Ferredoxin Reductase Antibody (Clone 6C2) 6216-100 Ferredoxin reductase is a ubiquitous flavoenzyme, containing noncovalently bound FAD as a prosthetic... 100 µl N/D
Ferredoxin Reductase Antibody (Clone 6C2) » Descripción

Ferredoxin reductase is a ubiquitous flavoenzyme, containing noncovalently bound FAD as a prosthetic group. It plays a role in delivering NADPH or low potential one-electron donors such as ferredoxin and flavodoxin to redox-based metabolisms in plastids, mitochondria and bacteria. In mammals, ferredoxin reductase is loosely associated with the inner mitochondrial membrane and receives electrons from NADPH. These electrons are transferred to ferredoxin which shuttles electrons to cytochrome P450 in the adrenal cortex mitochondrial steroid hydroxylation systems. It serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

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Shipping: gel pack, Storage Temp.: -20 °C

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WB

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Host & Isotype: Mouse IgG1, Species Reactivity: Human, Antibody Type: Monoclonal

Glutathione Peroxidase 3 Antibody (Clone 55A) 6215-100 Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of h... 100 µl N/D
Glutathione Peroxidase 3 Antibody (Clone 55A) » Descripción

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic /mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

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Shipping: gel pack, Storage Temp.: -20 °C

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IP: 1-2 µl, ELISA.

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Host & Isotype: Mouse IgG2b, Species Reactivity: Human, Antibody Type: Monoclonal

Glutathione Peroxidase 1 Antibody (Clone 2A10) 6214-100 Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of h... 100 µl N/D
Glutathione Peroxidase 1 Antibody (Clone 2A10) » Descripción

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic /mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

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Shipping: gel pack, Storage Temp.: -20 °C

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IP

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Host & Isotype: Mouse IgG1, Species Reactivity: Human, Antibody Type: Monoclonal

Glutathione Peroxidase 4 Antibody (Clone 1H11) 6213-100 Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of h... 100 µl N/D
Glutathione Peroxidase 4 Antibody (Clone 1H11) » Descripción

Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic /mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

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Shipping: gel pack, Storage Temp.: -20 °C

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IP: 1-2 µl, ELISA.

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Host & Isotype: Mouse IgG1, Species Reactivity: Human, mouse, rat, Antibody Type: Monoclonal

Glutathione Reductase Antibody (Clone 2B3) 6212-100 Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which inclu... 100 µl N/D
Glutathione Reductase Antibody (Clone 2B3) » Descripción

Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG). In most eukaryotic cells, GR maintains the ratio of [GSH]/[GSSG] elevated, and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.

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Shipping: gel pack, Storage Temp.: -20 °C

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IP: 1-2 µl, ELISA.

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Host & Isotype: Mouse IgG1, Species Reactivity: Human, Antibody Type: Monoclonal

Glutaredoxin 1 Antibody (Clone 28C3) 6211-100 Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs for... 100 µl N/D
Glutaredoxin 1 Antibody (Clone 28C3) » Descripción

Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxido-reductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12 kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress. Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

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Shipping: gel pack, Storage Temp.: -20 °C

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IP: 1-2 µl, ELISA.

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Host & Isotype: Mouse IgG1, Species Reactivity: Human, Antibody Type: Monoclonal

Proteinase K Antibody 6210-100 Proteinase K is a serine protease that displays the ability to digest native proteins, thereby inact... 100 µg N/D
Proteinase K Antibody » Descripción

Proteinase K is a serine protease that displays the ability to digest native proteins, thereby inactivating enzymes such as DNase and RNase without recourse to a denaturation process.

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Shipping: gel pack, Storage Temp.: -20 °C

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Western blotting (3-6 µg/ml)

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Host & Isotype: Rabbit IgG, Species Reactivity: Tritirachium album, Antibody Type: Polyclonal

UR144/XLR11, Synthetic Cannabinoids Antibody 6207-200 Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors on cells ... 200 µg N/D
UR144/XLR11, Synthetic Cannabinoids Antibody » Descripción

Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors on cells that repress neurotransmitter release in the brain. They are active chemicals in Cannabis that cause drug-like effects throughout the body, including the central nervous system and the immune system. Anti-UR144/XLR11 is a sheep polyclonal IgG antibody. It has been used in a competitive ELISA format to test the presence of UR-144 and XLR-11 and their metabolites in samples such as urine, whole blood, serum, and plasma (see Arntson et al, 2013). Note: If this antibody is used in an immunoassay to detect synthetic cannabinoids, suspect test samples must be confirmed using an alternative analytical method, for example LC-MS-MS.

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Shipping: gel pack, Storage Temp.: -20 °C

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ELISA (for 96-well plate coating use 1-3 μg/mL).

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Host & Isotype: Rabbit IgG, Species Reactivity: All species, Antibody Type: Polyclonal

JWH-250, Synthetic Cannabinoid Antibody 6206-200 Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors on cells ... 200 µg N/D
JWH-250, Synthetic Cannabinoid Antibody » Descripción

Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors on cells that repress neurotransmitter release in the brain. They are active chemicals in Cannabis that cause drug-like effects throughout the body, including the central nervous system and the immune system. Anti-JWH-250 is a rabbit polyclonal IgG antibody. It has been used in a competitive ELISA format to test the presence of JWH-250 and its metabolites in samples such as urine, whole blood, serum, and plasma (see Arntson et al, 2013). Note: If this antibody is used in an immunoassay to detect synthetic cannabinoids, suspect test samples must be confirmed using an alternative analytical method, for example LC-MS-MS.

» Información

Shipping: gel pack, Storage Temp.: -20 °C

» Más Datos

ELISA (for 96-well plate coating use 1-3 μg/mL).

» Extras

Host & Isotype: Rabbit IgG, Species Reactivity: All species, Antibody Type: Polyclonal

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